Coach Deion Sanders and the No. 19 Colorado Buffaloes are once again facing long odds as they go up against the No. 10 Oregon Ducks. Despite being underdogs, Coach Prime and the Buffaloes have exceeded expectations this season with a 3-0 record. On the other hand, the Ducks are also undefeated and are aiming to slow down the Colorado hype train in their pursuit of a College Football Playoff spot. The game will take place at Autzen Stadium with kickoff set for 3:30 p.m. ET. According to the latest odds from SportsLine, the Ducks are favored by 21 points with an over/under of 70.5. Before making any picks or bets, be sure to check out the insights and predictions from SportsLine football expert Jimmie Kaylor. Kaylor, a former NFL player and college football All-American, has been on fire with his Colorado picks this season, going 4-1 on his best bets in the Buffs’ first three games. He has now locked in his picks for the Colorado vs. Oregon matchup, which you can find on SportsLine.
Colorado vs. Oregon prediction, odds, spread, line, time: Top expert picks for Deion Sanders Pac-12 debut
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