Matthew Perry’s cause of death revealed as ‘acute effects of ketamine’

Matthew Perry’s official cause of death has been revealed, nearly two months after he was found dead at his California home on Oct. 28. The “Friends” actor was 54.

According to his autopsy report, the late star’s death was due to “acute effects of ketamine” and the manner is accidental drowning. He also had a history of coronary artery disease, the New York Post confirmed on Friday.

The “Fools Rush In” star was clean for 19 months but was on ketamine infusion therapy as recently as one and a half weeks before his death, the report concluded.

No drugs or loose pills were found near the pool of his residence, and there was no foul play.

As previously reported, he was found submerged underwater and facedown by a bystander before authorities were called and rushed to the scene.

Matthew Perry arrives at the GQ Men of the Year Party on Thursday, Nov.17, 2022, in West Hollywood. Willy Sanjuan/Invision/AP
Authorities placed a large white tent in Matthew Perry’s backyard when they arrived to his home on Oct. 28. WFLA
Perry’s family launched the Matthew Perry Foundation to help others with substance addictions after his death. WFLA

Per TMZ, Perry was found by his assistant at the time.

Perry was remembered by his family and “Friends” co-stars — Jennifer Aniston, Courteney Cox, Lisa Kudrow, David Schwimmer and Matt LeBlanc — on Nov. 3. He was laid to rest in the Forest Lawn cemetery in Hollywood Hills, Calif., which is located across from where “Friends” filmed for 10 years at Warner Bros.

Aniston, 54, recently revealed that she was in communication with Perry on the same day he died.

According to his autopsy report, the late star’s death was due to “acute effects of ketamine” and the manner is accidental drowning. Denver Post via Getty Images
No drugs or loose pills were found near the pool of Perry’s residence, and there was no foul play. AFP via Getty Images

“I was literally texting with him that morning, funny Matty,” she said in an interview with Variety through tears. “He was not in pain. He wasn’t struggling. He was happy.”

“He was happy,” the “Morning Show” actress recalled. “He was healthy. He had quit smoking. He was getting in shape. He was happy — that’s all I know.”

“I want people to know he was really healthy, and getting healthy,” Aniston added. “He was on a pursuit. He worked so hard. He really was dealt a tough one. I miss him dearly. We all do. Boy, he made us laugh really hard.”

Days after his death, the entire cast released a joint statement on his passing.

Matthew Perry at the premiere of “The Invention of Lying” in Los Angeles on Monday, Sept. 21, 2009. AP

“We are all so utterly devastated by the loss of Matthew. We were more than just cast mates. We are a family,” read their statement, obtained by People at the time. “There is so much to say, but right now we’re going to take a moment to grieve and process this unfathomable loss.”

“In time we will say more, as and when we are able,” the statement continued. “For now, our thoughts and our love are with Matty’s family, his friends, and everyone who loved him around the world.”

Co-creators of the sitcom Marta Kauffman and David Crane and executive producer Kevin Bright also spoke out following the tragic news.

“We are shocked and deeply, deeply saddened by our beloved friend Matthew’s passing,” they wrote. “It still seems impossible. All we can say is that we feel blessed to have had him as part of our lives. He was a brilliant talent.”

The “Friends” cast, Matt LeBlanc, Lisa Kudrow, David Schwimmer, Jennifer Aniston and Matthew Perry in 1994. NBCUniversal via Getty Images

“It’s a cliche to say that an actor makes a role their own, but in Matthew’s case, there are no truer words. From the day we first heard him embody the role of Chandler Bing, there was no one else for us,” the statement continued. “We will always cherish the joy, the light, the blinding intelligence he brought to every moment — not just to his work, but in life as well. He was always the funniest person in the room. More than that, he was the sweetest, with a giving and selfless heart.”

Their last words included a nod to how the “Friends” episode titles always began with “The One.”

“We send all of our love to his family and friends. This truly is The One Where Our Hearts Are Broken,” they concluded.

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